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Cardiac remodeling induced by smoking: concepts, relevance, and potential mechanisms
(Inflammation & Allergy Drug Targets, 2012)
Cardiac or ventricular remodeling is characterized by molecular, cellular, and interstitial alterations that lead to changes in heart size, mass, geometry and function in response to a given insult. Currently, tobacco smoke ...
Influence of different doses of retinoic acid on cardiac remodeling
(Elsevier B.V., 2011-07-01)
Objective: The role of retinoic acid in promoting postnatal heart alterations is still unclear. The aim of this study was to evaluate whether the cardiac alterations caused by all-trans- retinoic acid (ATRA) in normal adult ...
Physical training attenuates cardiac remodeling in rats with supra-aortic stenosis
(2014-01-01)
The aim of this study was to test the hypothesis that physical training (PT) attenuates cardiac remodeling and the severity of heart failure in rats with aortic stenosis. Wistar male rats were divided in sham (S, n=10), ...
Spondias mombin supplementation attenuated cardiac remodelling process induced by tobacco smoke
(2018-08-01)
The objective of this study was to investigate the influence of Spondias mombin (SM) supplementation on the cardiac remodelling process induced by exposure to tobacco smoke (ETS) in rats. Male Wistar rats were divided into ...
Pentoxifylline Attenuates Cardiac Remodeling Induced by Tobacco Smoke Exposure
(Arquivos Brasileiros Cardiologia, 2016-05-01)
Background: Tobacco smoke exposure is an important risk factor for cardiac remodeling. Under this condition, inflammation, oxidative stress, energy metabolism abnormalities, apoptosis, and hypertrophy are present. ...
Tobacco Smoke Induces Ventricular Remodeling Associated with an Increase in NADPH Oxidase Activity
(Karger, 2011-01-01)
Background: Recent studies have assessed the direct effects of smoking on cardiac remodeling and function. However, the mechanisms of these alterations remain unknown. The aim of this study was to investigate de role of ...
Lifetime Overproduction of Circulating Angiotensin-(1-7) Attenuates Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Dysfunction and Remodeling
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
We evaluated the development of arterial hypertension, cardiac function, and collagen deposition, as well as the level of components of the renin-angiotensin system in the heart of transgenic rats that overexpress an ...
Aerobic exercise training in heart failure: impact on sympathetic hyperactivity and cardiac and skeletal muscle function
(Associação Brasileira de Divulgação Científica, 2011)
Heart failure is a common endpoint for many forms of cardiovascular disease and a significant cause of morbidity and mortality. Chronic neurohumoral excitation (i.e., sympathetic hyperactivity) has been considered to be a ...
Effects of late exercise on cardiac remodeling and myocardial calcium handling proteins in rats with moderate and large size myocardial infarction
(2016-10-15)
Background Physical exercise attenuates myocardial infarction (MI)-induced cardiac remodeling. However, it is unsettled whether late exercise modulates post-infarction cardiac remodeling differentially according to infarct ...