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Pharmacokinetics and pharmacodynamics of antibiotics in critically ill acute kidney injury patients
(2016-12-01)
Sepsis is the most common cause of death in critically ill patients and is associated with multiorgan failure, including acute kidney injury (AKI). This situation can require acute renal support and increase mortality. ...
Acute kidney injury: risk factors and management challenges in developing countries
(Dove Medical Press Ltd, 2016-01-01)
Acute kidney injury (AKI) is a major global health problem in both developed and developing nations, negatively affecting patient morbidity and responsible for an estimated 1.4 million deaths per year. Although the ...
Effect of allopurinol on the kidney function, histology and injury biomarker (NGAL, IL 18) levels in uninephrectomised rats subjected to ischaemia-reperfusion injury
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-08-01)
PURPOSE: To investigate whether allopurinol exerts a protective effect on kidneys by measuring new kidney injury biomarkers (NGALp, NGALu, KIM 1 and IL 18) and analysing the renal function and histology in uninephrectomised ...
Good Outcomes in Kidney Transplantation With Deceased Donor With Acute Kidney Injury: Donor's Age and Not Acute Kidney Injury Predicts Graft Function
(2016-09-01)
Background With the increased demand for kidney transplants and the short supply of organs, it is necessary to have a better strategy to evaluate the available organs, especially from donors with acute kidney injury (AKI), ...
The effect of 6% Hydroxyethyl starch vs. Ringer's lactate on acute kidney injury after renal ischemia in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-01-01)
PURPOSE: To compare fluid replacement therapy with Hydroxyethyl starch 6% (HES) versus Ringer's lactate (RL) in a rodent model of non-septic renal ischemia. METHODS: Forty male Wistar rats were randomized to receive HES 2 ...
Reversal of acute kidney injury after peritoneal dialysis in a dog: a case report
(Czech Academy Agricultural Sciences, 2016-01-01)
Acute kidney injury is characterised by a sudden injury to the renal parenchyma and causes defects in its excretory, metabolic and endocrine function. Dialysis therapy has been instituted in small animal clinics with the ...
Factors associated with acute kidney injury in surgical patients at the intensive care unit
(Univ Federal Ceara, Dept Enfermagem, 2018-01-01)
Objective: to analyze factors associated with acute kidney injury in surgical patients at the intensive care unit. Methods: case-control study including survey of patient history records and a sample of 246 patients. For ...
Annexin 1 mimetic peptide protects against renal ischemia/reperfusion injury in rats
(SPRINGER, 2011)
Inflammation is currently recognized as a key mechanism in the pathogenesis of renal ischemia-reperfusion (I/R) injury. The importance of infiltrating neutrophil, lymphocytes, and macrophage in this kind of injury has been ...