Now showing items 1-10 of 25
Trophoblast cells primed with vasoactive intestinal peptide enhance monocyte migration and apoptotic cell clearance through αvβ3 integrin portal formation in a model of maternal-placental interaction
(Oxford University Press, 2015-05)
STUDY HYPOTHESIS: Is apoptotic cell phagocytosis by monocytes modulated by pathways elicited by vasoactive intestinal peptide (VIP) action on trophoblast? STUDY FINDING: Targeting trophoblast cells with VIP induces monocyte ...
Apoptotic index for prediction of postmolar gestational trophoblastic neoplasia
(Elsevier B.V., 2016-09-01)
BACKGROUND: Although 85% of patients with a complete hydatidiform mole achieve spontaneous remission after a few months, 15% of them will experience gestational trophoblastic neoplasia, which requires chemotherapy. To date, ...
Vasoactive Intestinal Peptide modulates trophoblast-derived cell line function and interaction with phagocytic cells through autocrine pathways
(Nature Publishing Group, 2016-05)
Trophoblast cells migrate and invade the decidual stroma in a tightly regulated process to maintain immune homeostasis at the maternal-placental interface during the first weeks of pregnancy. Locally synthesized factors ...
Caspase-8 activity is part of the BeWo trophoblast cell defense mechanisms against Trypanosoma cruzi infection
(Academic Press-Elsevier, 2016)
Congenital Chagas disease is caused by the protozoan parasite Trypanosoma cruzi that must cross the placental barrier during transmission. The trophoblast constitutes the first tissue in contact with the maternal-blood ...
Cell cycle and apoptosis in normal and cloned bovine near-term placentae
(ELSEVIER SCIENCE BV, 2009)
The bovine maternal epithelium is composed of cuboidal cells interspersed with low columnar cells having centrally located nuclei. Bovine trophoblast is composed of two cell types: mononuclear trophoblastic and giant ...
Cancer during pregnancy alters the activity of rat placenta and enhances the expression of cleaved PARP, cytochrome-c and caspase 3
(Biomed Central LtdLondonInglaterra, 2006)
A local innate immune response against Trypanosoma cruzi in the human placenta: The epithelial turnover of the trophoblast
(Academic Press, 2016)
Congenital Chagas disease, caused by Trypanosoma cruzi, is partially responsible for the progressive globalization of Chagas disease despite of its low transmission rate. The probability of congenital transmission depends ...
Mechanisms involved in p53 downregulation by leptin in trophoblastic cells
(W B Saunders Co Ltd, 2015-11)
Leptin, a 16-kDa polypeptide hormone, is produced by the adipocyte and can also be synthesized by placenta. We previously demonstrated that leptin promotes proliferation and survival in placenta, in part mediated by the ...
Caspase 8 inhibition increases the infection with trypanosoma cruzi in thehuman trophoblast cell line (bewo)
Congenital Chagas’ disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi), which is able to cross the placental barrier and infect both the placenta and fetus. However, congenital transmission ...
Leptin promotes cell proliferation and survival of trophoblastic cells
(Society for the Study of Reproduction, 2007-02)
Leptin, the 16-kDa protein product of the obese gene, was originally considered as an adipocyte-derived signaling molecule for the central control of metabolism. However, leptin has been suggested to be involved in other ...