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Polissacarídeos biodegradáveis úteis para a preparação de sistemas de liberação controlada de fármacos. Parte 1: Quitosana
(2002-12-01)
Due to an increasing interest, a vast number of biodegradable polymers have been obtained recently. Polymers naturally produced, such as cellulose, starch, chitosan and alginate, represent biodegradable materials, with low ...
Electrochemical, Spectrophotometric and Liquid-Chromatographic Approaches for Analysis of Tropical Disease Drugs
(Bentham Science Publ Ltd, 2009-02-01)
Drug analysis is important in several phases of drug development, such as formulation, stability studies and quality control. The importance of reliable analytical methods for drug determination in a fast, inexpensive, ...
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2007-03-01)
Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. However, no new classes of drugs for TB have been developed in the past 30 years. Therefore there is an ...
New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors
(Bentham Science Publ Ltd, 2005-10-01)
Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms ...
Chorismate synthase: An attractive target for drug development against orphan diseases
(2007-03-01)
The increase in incidence of infectious diseases worldwide, particularly in developing countries, is worrying. Each year, 14 million people are killed by infectious diseases, mainly HIV/AIDS, respiratory infections, malaria ...
Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus
(Wiley-Blackwell, 2013-01-01)
BackgroundNeuropsychiatric involvement in systemic lupus erythematosus (SLE) is complex and it is an important cause of morbidity and mortality. Management of nervous system manifestations of SLE remains unsatisfactory. ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Nanotechnology-based drug delivery systems for melanoma antitumoral therapy: a review
(Hindawi Publishing Corporation, 2015)
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA): molecular background, virulence, and relevance for public health
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2011-01-01)
Staphylococcus aureus and coagulase-negative Staphylococcus (CoNS) are frequently found in nosocomial environments as the main pathogen in several infections. In 1961, reports of nosocomial S. aureus resistant to methicillin, ...